Gallicchio Lisa, Miller Susan, Greene Teresa, Zacur Howard, Flaws Jodi A
From the Prevention and Research Center, the Weinberg Center for Women's Health & Medicine, Mercy Medical Center, Baltimore, Maryland; Department of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland; and Department of Veterinary Biosciences, University of Illinois, Urbana, Illinois.
Obstet Gynecol. 2009 May;113(5):1018-1026. doi: 10.1097/AOG.0b013e3181a1f906.
To test the hypothesis that cosmetologists are at increased risk of poor pregnancy outcomes compared with women of the same age who are not cosmetologists.
Participants were recruited through mass mailing of questionnaires. To be included in the study, respondents to the survey had to be aged between 21 and 55 years and not have had a hysterectomy or oophorectomy. This analysis focused on 350 cosmetologists and 397 women in other occupations who met these inclusion criteria and who reported five or fewer singleton pregnancies. The main outcome measures were miscarriage, stillbirth, the occurrence of maternal health conditions during pregnancy (preeclampsia, high blood pressure, diabetes), hospitalization or physician-ordered bed rest during pregnancy, preterm labor, and premature delivery (before 37 weeks at delivery).
There were no statistically significant associations between occupation and the pregnancy outcomes after adjustment for age, race, education, and smoking and alcohol use at the time of pregnancy. A statistically significant association was found between race and low birth weight such that nonwhite women were at increased risk of reporting a low birth weight neonate compared with white women (odds ratio [OR] 3.35, 95% confidence interval [CI] 1.53-7.26). Similarly, current smoking was found to be positively associated with miscarriage (OR 1.53, CI 1.09-2.16) and miscarriage or stillbirth (OR 1.64, 95% CI 1.18-2.28).
Risk of adverse pregnancy outcomes among cosmetologists is not increased compared with women of the same age working in other occupations.
检验这一假设,即与同龄的非美容师女性相比,美容师出现不良妊娠结局的风险更高。
通过大量邮寄调查问卷招募参与者。要纳入本研究,调查的受访者年龄必须在21至55岁之间,且未进行过子宫切除术或卵巢切除术。本分析聚焦于350名美容师以及397名从事其他职业且符合这些纳入标准、报告过五次或更少单胎妊娠的女性。主要结局指标包括流产、死产、孕期出现的母体健康状况(先兆子痫、高血压、糖尿病)、孕期住院或医生要求卧床休息、早产以及分娩孕周小于37周的早产。
在对年龄、种族、教育程度以及孕期吸烟和饮酒情况进行调整后,职业与妊娠结局之间不存在统计学显著关联。种族与低出生体重之间存在统计学显著关联,即与白人女性相比,非白人女性报告低出生体重新生儿的风险更高(优势比[OR]3.35,95%置信区间[CI]1.53 - 7.26)。同样,发现当前吸烟与流产(OR 1.53,CI 1.09 - 2.16)以及流产或死产(OR 1.64,95% CI 1.18 - 2.28)呈正相关。
与从事其他职业的同龄女性相比,美容师出现不良妊娠结局的风险并未增加。