使用红外成像评估搏动灌注期间尸体器官的活力。
Assessment of cadaveric organ viability during pulsatile perfusion using infrared imaging.
作者信息
Gorbach Alexander M, Leeser David B, Wang Hengliang, Tadaki Douglas K, Fernandez Carlos, Destephano David, Hale Douglas, Kirk Allan D, Gage Fred A, Elster Eric A
机构信息
Bioengineering and Physical Science, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA.
出版信息
Transplantation. 2009 Apr 27;87(8):1163-6. doi: 10.1097/TP.0b013e31819e3e02.
Assessment of pulsatile perfusion (PP) is limited to measurements of flow (V) and resistance (R). We investigated infrared (IR) imaging during PP as a means for precise organ assessment. IR was used to monitor 10 porcine kidneys during 18 hr of PP in an uncontrolled Donation after Cardiac Death model. An IR camera (Lockheed Martin) was focused on the anterior surfaces of the kidneys. The degree of temperature homogeneity was compared with standard measurements of V and R. IR thermal images correlated with V and R (R=0.92, P<0.001). IR detected an increase in homogeneity during PP by comparing standard deviation differences before and after PP (P=0.002), which was not evident by standard measurements of V and R. Finally, IR assessment allowed for measurement of dynamic changes in perfusion.
搏动灌注（PP）的评估仅限于流量（V）和阻力（R）的测量。我们研究了在搏动灌注期间进行红外（IR）成像，作为精确评估器官的一种方法。在心脏死亡后非控制性捐赠模型中，利用红外成像在18小时的搏动灌注过程中监测了10个猪肾。一台红外摄像机（洛克希德·马丁公司）聚焦于肾脏的前表面。将温度均匀度与流量和阻力的标准测量值进行比较。红外热图像与流量和阻力相关（R = 0.92，P < 0.001）。通过比较搏动灌注前后的标准差差异，红外成像检测到搏动灌注期间均匀度增加（P = 0.002），而这在流量和阻力的标准测量中并不明显。最后，红外评估能够测量灌注的动态变化。
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