Mertens J, Wellbrock M, Feidert F
Universitäts-HNO-Klinik Kiel.
HNO. 1991 Aug;39(8):307-10.
A total of 139 patients with nasal polyps were investigated by a standardized history, intradermal skin test and nasal challenge to house dust mite allergy. The aim of the study was to assess the disputed role of perennial allergy in patients with nasal polyps using allergens to the house dust mite as an example. Using our diagnostic criteria we found allergy to house dust mite in 28% of all cases. We found this diagnosis in 44.8% of patients aged 10-39. We recommend, especially in this age group, an allergy test, if necessary with the appropriate therapy. Test correlations are illustrated in 174 patients who have been examined by the above methods. Good reproducibility was found by the nasal challenge, which led to the right diagnosis in 92%, compared with 81% by a standardized history. Therefore, it can be considered to be the key to the diagnosis of allergy.
对139例鼻息肉患者进行了标准化病史调查、皮内皮肤试验和对屋尘螨过敏的鼻腔激发试验。本研究的目的是以屋尘螨变应原为例，评估常年性变应性在鼻息肉患者中存在争议的作用。根据我们的诊断标准，我们发现所有病例中有28%对屋尘螨过敏。在10 - 39岁的患者中，这一诊断率为44.8%。我们建议，尤其是在这个年龄组，如果有必要应进行变应性检测并给予适当治疗。对174例采用上述方法检查的患者进行了检测相关性分析。鼻腔激发试验具有良好的可重复性，其正确诊断率为92%，而标准化病史的正确诊断率为81%。因此，鼻腔激发试验可被视为变应性诊断的关键。
