Savel'ev L I, Kiiaev A V, Tsvirenko S V, Gerasimova L Iu
Klin Lab Diagn. 2009 Mar(3):34-6.
The informative value of a method for determining total antibodies (Ab) to thyroid-stimulating hormone receptor (TSHR) in the diagnosis of Graves' disease was evaluated in 80 children with various causes of hyperthyroidism. With a RSHR Ab of > 1.6 IU/l, the diagnostic sensitivity and specificity of the test were 100%. Patients with hyperthyroidism and no RSHR Ab require no active therapeutic intervention and need to be followed up.