基因组扫描检测到影响丹麦和瑞典荷斯坦奶牛雌性繁殖性状的数量性状位点。

Genome scan detects quantitative trait loci affecting female fertility traits in Danish and Swedish Holstein cattle.

作者信息

Höglund J K, Guldbrandtsen B, Su G, Thomsen B, Lund M S

机构信息

Aarhus University, Faculty of Agricultural Sciences, Department of Genetics and Biotechnology, PO Box 50, 8830 Tjele, Denmark.

出版信息

J Dairy Sci. 2009 May;92(5):2136-43. doi: 10.3168/jds.2008-1104.

DOI:10.3168/jds.2008-1104

PMID:19389971

Abstract

Data from the joint Nordic breeding value prediction for Danish and Swedish Holstein grandsire families were used to locate quantitative trait loci (QTL) for female fertility traits in Danish and Swedish Holstein cattle. Up to 36 Holstein grandsires with over 2,000 sons were genotyped for 416 microsatellite markers. Single trait breeding values were used for 12 traits relating to female fertility and female reproductive disorders. Data were analyzed by least squares regression analysis within and across families. Twenty-six QTL were detected on 17 different chromosomes. The best evidence was found for QTL segregating on Bos taurus chromosome (BTA)1, BTA7, BTA10, and BTA26. On each of these chromosomes, several QTL were detected affecting more than one of the fertility traits investigated in this study. Evidence for segregation of additional QTL on BTA2, BTA9, and BTA24 was found.

摘要

来自丹麦和瑞典荷斯坦公牛家族的北欧联合育种值预测数据被用于定位丹麦和瑞典荷斯坦奶牛雌性繁殖性状的数量性状基因座（QTL）。对多达36头拥有超过2000头儿子的荷斯坦公牛进行了416个微卫星标记的基因分型。单性状育种值用于12个与雌性繁殖力和雌性生殖障碍相关的性状。通过家族内和家族间的最小二乘回归分析对数据进行了分析。在17条不同的染色体上检测到了26个QTL。在牛（Bos taurus）染色体（BTA）1、BTA7、BTA10和BTA26上发现了QTL分离的最佳证据。在这些染色体的每一条上，都检测到了几个影响本研究中调查的多个繁殖性状的QTL。还发现了BTA2、BTA9和BTA24上存在其他QTL分离的证据。