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与新生儿高胆红素血症换血治疗相关的不良事件。

Adverse events associated with neonatal exchange transfusion for hyperbilirubinemia.

作者信息

Behjati Sh, Sagheb S, Aryasepehr S, Yaghmai B

机构信息

Neonatal Department, Children Hospital Medical Center, Tehran, Iran.

出版信息

Indian J Pediatr. 2009 Jan;76(1):83-5. doi: 10.1007/s12098-009-0033-1. Epub 2009 Apr 18.

DOI:10.1007/s12098-009-0033-1
PMID:19391007
Abstract

To estimate the incidence of blood exchange and determine causes and complication of blood exchange and identify strategies for risk reduction of Kernicterus in newborn with jaundice. From March 2004 to March 2006 in neonatal Department in children hospital, medical center Tehran, Iran, 346 neonates were admitted as neonatal jaundice without sign and symptoms of infections. We identified causes and complications of exchange. Of 346 infants with jaundice who received phototherapy. 50, 14.45 percent cases underwent exchange transfusion with mean age 9.38 + 5.75 days. The mean total Serum bilirubin level was 29.39 + 6.13 mg/dl. ABO incompatibility was the most common cause for hyperbilirubinemia. The incidence of apnea was 12% there was no direct death from exchange transfusion. To make payment women aware to observe jaundice regularly after birth of their child and short breast feeding to control dehydration.

摘要

评估换血发生率,确定换血的原因及并发症,并确定降低新生儿黄疸核黄疸风险的策略。2004年3月至2006年3月,在伊朗德黑兰医疗中心儿童医院新生儿科,346例新生儿因新生儿黄疸入院,无感染体征和症状。我们确定了换血的原因和并发症。在346例接受光疗的黄疸婴儿中,50例(14.45%)接受了换血治疗,平均年龄为9.38±5.75天。血清总胆红素平均水平为29.39±6.13mg/dl。ABO血型不合是高胆红素血症最常见的原因。呼吸暂停发生率为12%,换血治疗无直接死亡病例。让产妇了解在孩子出生后定期观察黄疸情况以及缩短母乳喂养以控制脱水。

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Bilirubin toxicity to human erythrocytes: a review.胆红素对人红细胞的毒性:综述
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