药物性中毒性表皮坏死松解症和史蒂文斯-约翰逊综合征。

Prescrire Int. 2009 Feb;18(99):20-2.

Lyell syndrome is characterised by toxic epidermal necrolysis in which epidermal detachment affects more than 30% of the body surface area. Stevens-Johnson syndrome is a minor form affecting less than 10% of the body surface area; 2) Patients who present with these cutaneous symptoms, along with throat pain, red eyes and a damaged or detached oral mucosa must be hospitalised immediately; 3) Lyell syndrome is exclusively caused by drugs while Stevens-Johnson syndrome can also be caused by bacteria and viruses. Rapid withdrawal of the drug improves prognosis.

莱尔综合征的特征是中毒性表皮坏死松解症，其中表皮剥脱面积超过体表面积的30%。史蒂文斯-约翰逊综合征是一种较轻的形式，累及体表面积不到10%；2) 出现这些皮肤症状，同时伴有咽痛、眼红以及口腔黏膜受损或剥脱的患者必须立即住院；3) 莱尔综合征仅由药物引起，而史蒂文斯-约翰逊综合征也可由细菌和病毒引起。迅速停用药物可改善预后。

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Prescrire Int. 2009 Feb;18(99):20-2.

Lyell syndrome is characterised by toxic epidermal necrolysis in which epidermal detachment affects more than 30% of the body surface area. Stevens-Johnson syndrome is a minor form affecting less than 10% of the body surface area; 2) Patients who present with these cutaneous symptoms, along with throat pain, red eyes and a damaged or detached oral mucosa must be hospitalised immediately; 3) Lyell syndrome is exclusively caused by drugs while Stevens-Johnson syndrome can also be caused by bacteria and viruses. Rapid withdrawal of the drug improves prognosis.

莱尔综合征的特征是中毒性表皮坏死松解症，其中表皮剥脱面积超过体表面积的30%。史蒂文斯-约翰逊综合征是一种较轻的形式，累及体表面积不到10%；2) 出现这些皮肤症状，同时伴有咽痛、眼红以及口腔黏膜受损或剥脱的患者必须立即住院；3) 莱尔综合征仅由药物引起，而史蒂文斯-约翰逊综合征也可由细菌和病毒引起。迅速停用药物可改善预后。