Lombardi C, Incorvaia C, Braga M, Senna G, Canonica G W, Passalacqua G
Pneumoallergology Unit, S. Orsola FBF Hospital, Brescia, Italy.
Allergy. 2009 Jun;64(6):849-54. doi: 10.1111/j.1398-9995.2009.02063.x. Epub 2009 Apr 14.
The modalities of administration of sublingual immunotherapy (SLIT), including dosing, build-up phase, duration of the treatment, and frequency of the maintenance dose are largely variable. In the case of pollen (SLIT), the complexity increases, since preseasonal, coseasonal and pre-coseasonal regimens can be used. The administration regimens are of relevance from a practical point of view, but can also have economic implications. We review herein the available literature (randomized double blind controlled studies) on pollen SLIT, in order to derive experimentally-supported suggestions about the regimens of administration that should be preferred.
舌下免疫疗法（SLIT）的给药方式，包括剂量、累积阶段、治疗持续时间和维持剂量的频率，差异很大。对于花粉（SLIT），情况更为复杂，因为可以采用季前、季中及季前-季中联合治疗方案。从实际角度来看，给药方案很重要，同时也可能产生经济影响。我们在此回顾了关于花粉SLIT的现有文献（随机双盲对照研究），以便得出关于应优先选择的给药方案的实验支持建议。
