Meagher A P, Lord R S, Graham A R, Hill D A
Surgical Professional Unit, University of New South Wales, St. Vincent's Hospital, Sydney, Australia.
J Cardiovasc Surg (Torino). 1991 Sep-Oct;32(5):643-7.
In a two year period eight patients have presented with acute aortic occlusion and a poor outcome in seven. Initial failure to diagnose aortic occlusion, with a mean delay from presentation to diagnosis of 24 hours, was mainly responsible. All patients had varying degrees of paralysis on presentation which misled clinicians although other findings of acute ischaemia (pain, absent pulses, colour change and anaesthesia) were always present. Two patients were initially referred to a neurologist, another to a neurosurgeon, and the fourth to an orthopaedic surgeon. Even after diagnosis had been established, the need for urgent revascularization was not always recognized, the mean time from diagnosis to revascularization being 13 hours. Unnecessary aortography contributed to this delay in four patients. In two patients operative treatment was not undertaken while six were treated operatively by: aortic bifurcation graft (3), aortic thromboendarterectomy and femoropopliteal bypass (1), open aortic embolectomy (1) and bilateral femoral embolectomy (1). The causes of aortic occlusion were thrombosis of an atherosclerotic aorta (5), thrombosis of an aneurysm (2) and embolism (1). In the latter patient, the heparin induced thrombocytopenia syndrome (HITS) was primarily responsible. The outcomes in the eight patients were death (5), paraplegia (1), amputation (1), and uncomplicated recovery (1). The single patient who made an uncomplicated recovery had the shortest delay from presentation to revascularization of only 2 1/4 hours. Acute aortic occlusion rivals aortic rupture as a vascular emergency and demands immediate operative intervention.
在两年时间里,有8例患者出现急性主动脉闭塞,其中7例预后不良。主要原因是最初未能诊断出主动脉闭塞,从出现症状到确诊的平均延迟时间为24小时。所有患者就诊时均有不同程度的瘫痪,这误导了临床医生,尽管急性缺血的其他表现(疼痛、脉搏消失、肤色改变和感觉缺失)始终存在。2例患者最初被转诊给神经科医生,另1例被转诊给神经外科医生,第4例被转诊给骨科医生。即使确诊后,也并非总能认识到紧急血管重建的必要性,从确诊到血管重建的平均时间为13小时。4例患者因不必要的主动脉造影导致了这种延迟。2例患者未接受手术治疗,6例接受了手术治疗,手术方式包括:主动脉分叉移植术(3例)、主动脉血栓内膜切除术及股腘动脉搭桥术(1例)、开放性主动脉栓子切除术(1例)和双侧股动脉栓子切除术(1例)。主动脉闭塞的原因包括动脉粥样硬化性主动脉血栓形成(5例)、动脉瘤血栓形成(2例)和栓塞(1例)。在后者患者中,肝素诱导的血小板减少综合征(HITS)是主要原因。8例患者的预后为死亡(5例)、截瘫(1例)、截肢(1例)和无并发症康复(1例)。唯一无并发症康复的患者从出现症状到血管重建的延迟时间最短,仅为2.25小时。急性主动脉闭塞作为一种血管急症,与主动脉破裂相当,需要立即进行手术干预。