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在术前接受PET/CT评估动脉瘤壁病理的患者中偶然发现恶性肿瘤。

Incidental finding of malignancy in patients preoperatively evaluated for aneurysm wall pathology using PET/CT.

作者信息

Truijers Maarten, Pol Jillis A, Kurvers Harrie, Bredie Sebastian, Oyen Wim J, Blankensteijn Jan D

机构信息

Department of Surgery and Vascular Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

出版信息

J Vasc Surg. 2009 May;49(5):1313-5. doi: 10.1016/j.jvs.2008.12.001.

Abstract

Preoperative positron emission tomography/computed tomography (PET/CT) was performed in 26 consecutive patients considered fit for aneurysm repair. Besides information on aneurysm wall pathology, PET/CT identified 6 patients with concomitant malignancy. As a result of this coincidental finding, the operation was postponed in 2 patients and cancelled in 1. Although previous studies have shown that PET/CT might affect patient selection based on aneurysm wall inflammation, our preliminary results show a big impact on patient management as a result of the sensitivity of PET/CT for detecting malignancy. Future larger studies are warranted to investigate the effect and cost effectiveness of routine PET/CT in abdominal aortic aneurysm (AAA) patients.

摘要

对连续26例被认为适合动脉瘤修复的患者进行了术前正电子发射断层扫描/计算机断层扫描(PET/CT)。除了提供有关动脉瘤壁病理的信息外,PET/CT还发现了6例合并恶性肿瘤的患者。由于这一偶然发现,2例患者的手术被推迟,1例患者的手术被取消。尽管先前的研究表明PET/CT可能会基于动脉瘤壁炎症影响患者的选择,但我们的初步结果显示,由于PET/CT检测恶性肿瘤的敏感性,其对患者管理有很大影响。有必要开展未来更大规模的研究,以调查常规PET/CT在腹主动脉瘤(AAA)患者中的效果和成本效益。

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