Ekmektzoglou Konstantinos A, Xanthos Theodoros, German Vasilios, Zografos Georgios C
Department of Experimental Surgery and Surgical Research N.S. Christeas, University of Athens, Medical School, Athens, Greece.
Eur J Obstet Gynecol Reprod Biol. 2009 Jul;145(1):3-8. doi: 10.1016/j.ejogrb.2009.03.017. Epub 2009 Apr 25.
Breast cancer is a daunting disease and constitutes a continuing medical health problem through the ages for millions of women worldwide. Physicians, from the early periods of recorded history have tried to heal breast cancer patients, with results that were fairly promising at times and disappointing at others. The science of medicine evolved through the ages under the careful scrutiny and critical thought of the many prominent scholars and researchers of their times who constantly added to the therapeutic armamentarium. Surgeons described new therapeutic approaches, and anatomists, through their elaborate descriptions, added useful insights on the art of healing. Theories about the origin of cancer change as new scientific data are presented and validated. Although the Middle Ages hindered temporarily any progress in the field of medicine, the Renaissance became the vaulting horse for science in its broadest sense. However, it was not until the 19th century, with the discovery of anesthesia, the introduction of antisepsis, and the establishment of microscopy that giant scientific leaps in the field of breast cancer treatment occurred. The 20th century with the development of chemotherapy and radiation and the undertaking of numerous clinical trials offered new insights regarding breast cancer management. This article attempts a historical journey through the ages unfolding the problem of breast cancer through the different eras.
乳腺癌是一种令人生畏的疾病,千百年来一直是全球数百万女性持续面临的医疗健康问题。从有历史记载的早期开始,医生们就试图治愈乳腺癌患者,治疗结果有时相当可观,有时却令人失望。随着岁月的流逝,医学在当时众多杰出学者和研究人员的仔细审视和批判性思考下不断发展,他们不断丰富着治疗手段。外科医生描述了新的治疗方法,解剖学家通过详尽的描述,为治疗技艺提供了有益的见解。随着新的科学数据被提出并得到验证,关于癌症起源的理论也在不断变化。尽管中世纪暂时阻碍了医学领域的任何进步,但文艺复兴成为了广义科学的助推器。然而,直到19世纪,随着麻醉术的发现、防腐技术的引入以及显微镜技术的建立,乳腺癌治疗领域才实现了巨大的科学飞跃。20世纪,随着化疗和放疗的发展以及众多临床试验的开展,为乳腺癌的管理提供了新的见解。本文试图展开一段穿越历史的旅程,呈现不同时代下乳腺癌问题的发展历程。