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[骨折与愈合机制。从牵张成骨角度看骨折愈合的机械应力]

[Bone fracture and the healing mechanisms. The mechanical stress for fracture healing in view of distraction osteogenesis].

作者信息

Yukata Kiminori, Takahashi Mitsuhiko, Yasui Natsuo

机构信息

Department of Orthopedics, Institute of Health Biosciences, The University of Tokushima Graduate School.

出版信息

Clin Calcium. 2009 May;19(5):641-6.

Abstract

It is generally accepted that moderate mechanical stress influences the course of fracture healing. A flexible fixation of the fractured site can induce fracture callus formation, whereas an unstable fixation can lead to a nonunion. The relationship between mechanical stress and the process of bone regeneration or healing remains incompletely understood. Distraction osteogenesis is a surgical technique that, using appropriate mechanical tension-stress, does not break the callus but rather it stimulates and maintains osteogenesis. The common principles of distraction osteogenesis are osteotomy and slow progressive distraction by an external fixation device. Interest in bone regeneration associated with mechanical stress might lead to better understanding of the fracture healing process.

摘要

一般认为,适度的机械应力会影响骨折愈合的进程。对骨折部位进行柔性固定可诱导骨折骨痂形成,而不稳定固定则可能导致骨不连。机械应力与骨再生或愈合过程之间的关系仍未完全明了。牵张成骨术是一种外科技术,通过施加适当的机械张应力,不会破坏骨痂,反而能刺激并维持成骨作用。牵张成骨术的共同原则是截骨术以及通过外固定装置进行缓慢渐进性牵张。对与机械应力相关的骨再生的关注可能会增进对骨折愈合过程的理解。

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