Suppr超能文献

牵张成骨与对接部位骨不连:是否存在理想的治疗选择?

Distraction osteogenesis and nonunion of the docking site: is there an ideal treatment option?

作者信息

Giotakis Nikolaos, Narayan Badri, Nayagam Selvadurai

机构信息

Department of Trauma & Orthopaedics, Royal Liverpool and Broadgreen University Hospital, Liverpool, UK.

出版信息

Injury. 2007 Mar;38 Suppl 1:S100-7. doi: 10.1016/j.injury.2007.02.015.

Abstract

Docking sites are the result of a classic bone transport technique for dealing with bone loss. Union may prove to be the rate-limiting step in the duration of treatment. Strategies to improve union have focused on surgical manipulation such as immediate coaptation of the margins of the segmental defect in the process of acute shortening to prevent fibrocartilaginous capping of the ends of bone during transport. This procedure has the highest success rate for union but is limited by its effect on the limb's vascularity. Other techniques for improving union involve compression, alternate compression-distraction, and bone grafts, all of which induce union to a variable degree. The application of external stimulators and bone morphogenetic proteins, the use of which is supported in fracture healing and even regenerate formation, is as yet unproven at docking sites.

摘要

对接部位是一种经典的骨搬运技术治疗骨缺损的结果。骨愈合可能是治疗持续时间中的限速步骤。改善骨愈合的策略集中在手术操作上,例如在急性缩短过程中立即对节段性缺损边缘进行对接,以防止在骨搬运过程中骨端形成纤维软骨帽。该手术骨愈合成功率最高,但受其对肢体血运影响的限制。其他改善骨愈合的技术包括加压、交替加压-撑开以及骨移植,所有这些技术都能在不同程度上促进骨愈合。外部刺激器和骨形态发生蛋白的应用在骨折愈合甚至再生形成中得到支持,但在对接部位的应用尚未得到证实。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验