Salman M C, Usubutun A, Dogan N U, Yuce K
Department of Obstetrics and Gynaecology, Division of Gynaecological Oncology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Clin Exp Obstet Gynecol. 2009;36(1):31-4.
To evaluate the accuracy of frozen section analysis in patients with atypical endometrial hyperplasia.
Women who underwent hysterectomy with frozen section analysis for atypical endometrial hyperplasia were identified. Frozen section evaluation aimed to give information about the presence of malignancy. Also, myometrial or cervical involvement was assessed in cases with malignancy to reveal the need for staging. Final pathological evaluation results were compared with intraoperative frozen section analyses.
Twelve patients (34.3%) had endometrial cancer on final pathologic examination and eight required a staging procedure due to either myometrial invasion or cervical involvement; 75% of patients with endometrial cancer were successfully detected by frozen section analysis. Moreover, among women with cancer, frozen section examination revealed 75% of cases who required surgical staging.
Frozen section analysis of hysterectomy specimens in patients with atypical endometrial hyperplasia is necessary to determine the presence of cancer and the need for surgical staging.
评估冷冻切片分析在非典型子宫内膜增生患者中的准确性。
确定接受了因非典型子宫内膜增生而行冷冻切片分析的子宫切除术的女性。冷冻切片评估旨在提供有关恶性肿瘤存在的信息。此外，对恶性肿瘤病例评估肌层或宫颈受累情况以确定分期的必要性。将最终病理评估结果与术中冷冻切片分析进行比较。
12例患者（34.3%）最终病理检查诊断为子宫内膜癌，其中8例因肌层浸润或宫颈受累需要进行分期手术；冷冻切片分析成功检测出75%的子宫内膜癌患者。此外，在患有癌症的女性中，冷冻切片检查发现75%的病例需要手术分期。
对于非典型子宫内膜增生患者，子宫切除标本的冷冻切片分析对于确定癌症的存在和手术分期的必要性是必要的。
