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充血性心力衰竭和肾脏并发症。

Congestive heart failure and renal complications.

作者信息

Del Rio-Santiago Valentin J, Rodriguez-Ospina Luis, Córdova Héctor R, Vicenty Sonia I

机构信息

Cardiology Section, Department of Medicine, VA Caribbean Healthcare System, Puerto Rico, USA.

出版信息

Bol Asoc Med P R. 2008 Oct-Dec;100(4):29-37.

Abstract

Congestive heart failure is the leading cause of hospital admission among patients over the age of 65 years. It affects population within the United States, including Puerto Rico, presenting itself as the leading cause of heart related deaths worldwide. Its management can include pharmacologic agents which will affect neuroendocrine axis mainly but also include novel non-pharmacologic approaches such as ultrafiltration. The coexistence of heart failure and renal dysfunctions are very common within our medical community, especially within the western hemisphere, causing greater concerns amongst the medical field with increased research and investigation activity. This clinical review article will address the theme of congestive heart failure, highlighting the edema formation concept, volume homeostasis, cardio-renal syndrome and neuroendocrine pathways. The management of acute decompensated heart failure is discussed, primarily focusing with available novel non-pharmacologic approaches.

摘要

充血性心力衰竭是65岁以上患者住院的主要原因。它影响包括波多黎各在内的美国人群,是全球心脏相关死亡的主要原因。其治疗可包括主要影响神经内分泌轴的药物制剂,但也包括诸如超滤等新型非药物方法。心力衰竭和肾功能不全的共存在我们的医学界非常常见,尤其是在西半球,这引起了医学领域越来越多的关注,研究和调查活动也日益增多。这篇临床综述文章将探讨充血性心力衰竭这一主题,重点介绍水肿形成概念、容量稳态、心肾综合征和神经内分泌途径。本文讨论了急性失代偿性心力衰竭的治疗,主要关注现有的新型非药物方法。

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