Department of Internal Medicine I, University of Regensburg, Regensburg, Germany.
Eur J Gastroenterol Hepatol. 2009 Aug;21(8):952-4. doi: 10.1097/MEG.0b013e3283200088.
An 18-year-old male experienced a first episode of Crohn's disease with inflammation of the colon, stenosis of small intestine and a fistula of the anal sphincter. After resection of the fistula and 30 cm of proximal ileum the patient remained free of symptoms under medication with azathioprine and mesalazine for 6 years. Then, blood in the stool occurred. Diagnostic work-up - gastroscopy and colonoscopy 2004 and 2006, magnetic resonance enteroclysis 2004 and 2006 and wireless capsule enteroscopy 2006 - revealed slight inflammation in the ileum but no bleeding source. The bleeding ceased, but after 2 uneventful years abdominal cramps appeared and diagnostic work-up (magnetic resonance enteroclysis, radiograph) located the capsule still in the terminal ileum proximal to an inflamed stenosis. Corticosteroids were subscribed for 4 weeks, but the capsule stayed in place. Surgery was discussed, but denied by the patient. Finally, the capsule could be taken out by double balloon enteroscopy.
一位 18 岁男性首次出现克罗恩病,病变累及结肠、小肠狭窄和肛门括约肌瘘。瘘管切除和近端回肠 30cm 切除后,患者在接受巯嘌呤和美沙拉嗪治疗 6 年后无任何症状。之后,出现便血。诊断性检查——2004 年和 2006 年的胃镜和结肠镜检查、2004 年和 2006 年的磁共振肠造影检查和 2006 年的无线胶囊内镜检查——显示回肠有轻微炎症,但未发现出血源。出血停止,但在 2 年无并发症后,出现腹痛,诊断性检查(磁共振肠造影、射线照相)发现胶囊仍位于末端回肠近端的炎症性狭窄处。患者接受了 4 周的皮质类固醇治疗,但胶囊仍在原位。曾讨论手术治疗,但被患者拒绝。最终,双气囊内镜取出了胶囊。