Department of Hepatogastroenterology, Rouen University Hospital, France.
Eur J Gastroenterol Hepatol. 2009 Jul;21(7):827-9. doi: 10.1097/MEG.0b013e3282ff0f6f.
We report the case of a 77-year-old man referred for jaundice and diagnosed with intrahepatic light chain deposit as primary manifestation of a kappa light chain multiple myeloma. Jaundice is a very rare way of presentation for myeloma. In our observation, diagnosis was made by liver biopsy, which found light chain deposits infiltrating perisinusoidal spaces. We discuss jaundice's possible mechanisms in myeloma.
我们报告了一例 77 岁男性因黄疸就诊,被诊断为以κ轻链多发性骨髓瘤为主要表现的肝内轻链沉积症。黄疸是骨髓瘤非常罕见的表现形式。在我们的观察中,通过肝脏活检做出了诊断,活检发现轻链沉积物浸润窦周间隙。我们讨论了骨髓瘤中黄疸的可能机制。