估计肾小球滤过率：是时候进行性能评估了吗？
Estimated glomerular filtration rate: time for a performance review?
作者信息
Glassock Richard J
机构信息
Geffen School of Medicine at UCLA, Los Angeles, California, USA.
出版信息
Kidney Int. 2009 May;75(10):1001-3. doi: 10.1038/ki.2009.38.
Measurement of the glomerular filtration rate (GFR) is an essential element in assessing renal function. Formulaic estimations of GFR (eGFRs) are widely used but have many pitfalls. Application of eGFR without adjustment for the effects of aging and gender results in overdiagnosis of chronic kidney disease (CKD). eGFR formulae also contain variables that independently influence the risk of CKD and cardiovascular disease. eGFR needs a performance review to foster its evolution as a clinically useful tool.
肾小球滤过率（GFR）的测量是评估肾功能的一个重要因素。GFR的公式估算（eGFR）被广泛使用，但存在许多缺陷。在不针对年龄和性别影响进行调整的情况下应用eGFR会导致慢性肾脏病（CKD）的过度诊断。eGFR公式还包含独立影响CKD和心血管疾病风险的变量。eGFR需要进行性能评估，以促进其作为一种临床有用工具的发展。
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