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[选择性肺动脉阻断试验(SPAO)条件下肺叶切除术的心肺功能评估]

[Evaluation of cardio-pulmonary function for lobectomy under the condition of selective pulmonary arterial occlusion test (SPAO)].

作者信息

Suzuki S, Tanita T, Koike K, Ashino Y, Nasu G, Kubo H, Shibuya J, Iwabuchi S, Fujimura S

机构信息

Department of Surgery, Tohoku University, Sendai, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1991 Aug;39(8):1147-52.

PMID:1940516
Abstract

We performed selective pulmonary arterial occlusion test (SPAO) and unilateral pulmonary arterial occlusion test (UPAO) in 30 patients with lung cancer who would be undertaken right lower lobectomy or middle and lower lobectomy, and evaluated the preoperative cardio-pulmonary function. The lung hemodynamics during SPAO were different from those during UPAO. This indicates that SPAO evaluated reserve capacity of vascular bed in the right upper lobe which would be remained at the surgery. Moreover, the ratio of total pulmonary vascular resistance during SPAO to that of before SPAO was not differed in two groups, one was a group with and the other was a group without impaired reserve capacity of vascular bed in the contralateral lung. This suggests that reserve capacity of pulmonary vascular bed including right upper lobe would be well compensated even in the patients with highly impaired capacity in the contralateral lung. Based on these findings, we performed lung resections in 9 patients, who were judged contraindications for lung resection by the results of UPAO, and no patient suffered postoperative cardio-pulmonary complications. Total pulmonary vascular resistance immediately after the right middle and lower lobectomy were equal to those during SPAO. Thus we conclude that SPAO is very useful technique for evaluating cardiopulmonary function after right lower lobectomy or middle and lower lobectomy, and that it would be possible to extend the boundaries of safety for lung resection based on evaluation of cardio-pulmonary function by SPAO.

摘要

我们对30例拟行右下肺叶切除术或中下肺叶切除术的肺癌患者进行了选择性肺动脉闭塞试验(SPAO)和单侧肺动脉闭塞试验(UPAO),并评估了术前心肺功能。SPAO期间的肺血流动力学与UPAO期间不同。这表明SPAO评估了手术中会保留的右上叶血管床的储备能力。此外,在两组中,SPAO期间的总肺血管阻力与SPAO前的总肺血管阻力之比无差异,一组对侧肺血管床储备能力受损,另一组对侧肺血管床储备能力未受损。这表明,即使对侧肺功能严重受损的患者,包括右上叶在内的肺血管床储备能力也能得到良好的代偿。基于这些发现,我们对9例根据UPAO结果被判定为肺切除禁忌证的患者进行了肺切除术,无一例患者出现术后心肺并发症。右下中肺叶切除术后立即测得的总肺血管阻力与SPAO期间相等。因此,我们得出结论,SPAO是评估右下肺叶切除术或中下肺叶切除术后心肺功能的非常有用的技术,并且基于SPAO对心肺功能的评估,有可能扩大肺切除的安全范围。

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