Balla R, LoMonaco C J, Skribner J, Lin L M
Department of Endodontics, University of Medicine and Dentistry, New Jersey Dental School, Newark.
J Endod. 1991 May;17(5):234-8. doi: 10.1016/S0099-2399(06)81928-X.
One-hundred twenty experimental furcation perforations were created in the mandibular and maxillary premolars and molars of six rhesus monkeys. Tricalcium phosphate, hydroxylapatite, amalgam, and Life were used to repair the furcation perforations. The animals were sacrificed at the intervals of 2, 4, and 6 months after the experiment. Histological evaluation revealed lack of complete healing of furcation perforations repaired with any materials. Epithelium was present in the furcation perforations in both experimental and positive control groups. No hard tissue formation was observed in this study. Inflammation in the furcation area may be due to inadequate sealing ability of the repair materials.
在六只恒河猴的下颌和上颌前磨牙及磨牙上制造了120个实验性根分叉穿孔。使用磷酸三钙、羟基磷灰石、汞合金和Life材料修复根分叉穿孔。实验后分别在2个月、4个月和6个月处死动物。组织学评估显示,用任何材料修复的根分叉穿孔均未完全愈合。实验组和阳性对照组的根分叉穿孔处均有上皮组织。本研究未观察到硬组织形成。根分叉区域的炎症可能是由于修复材料的封闭能力不足所致。