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[医学隆鼻术:使用肉毒杆菌毒素和填充剂进行无创鼻塑形的原理]

[Medical rhinoplasty: rationale for atraumatic nasal modelling using botulinum toxin and fillers].

作者信息

Braccini F, Dohan Ehrenfest D M

机构信息

ORL, Chirurgie Face et Cou, 25 avenue Jean Médecin, F-06000 Nice, France.

出版信息

Rev Laryngol Otol Rhinol (Bord). 2008;129(4-5):233-8.

PMID:19408501
Abstract

OBJECTIVES

To describe the new techniques for medical rhinoplasty, associating fillers and botulinum toxin without invasive surgery, to evaluate their efficiency with a retrospective analysis on 85 patients for 2 years, and to discuss the adequate indications for this new approach.

MATERIAL AND METHODS

Between january 2006 and january 2008, 85 patients were treated using a non surgical approach for aesthetic disorders of the nasal pyramid. 62 women and 23 men were included, with different indications: 32 primary rhinoplasties, 53 secondary rhinoplasty corrections. Fillers were used alone in 58 cases, botulinum toxin alone in 12 cases, and both products were used together in 15 cases. Botulinum toxin was always an A-type toxin. For fillers, reticulated hyaluronic acid was used in 56 cases, calcium hydroxyapatite in 11 cases, tricalcium phosphate in 2 cases, L-polylactic acid in 2 cases and polyacrylamid gel in 2 cases. Fillers were injected after application of anaesthetic gel, and placed in depth with osteocartilaginous contact following a retro-tracing movement. At the end of the procedure, the nose was manually modelled in order to improve the product distribution. Botulinum toxin injection was performed without anaesthesia following a specific protocol. Clinical results were evaluated by the patient and the physician immediately after treatment, after 15 days and after 1 month. The satisfaction index was based on 3 answers after 1 month: very satisfactory, satisfactory, insufficient.

RESULTS

In this series of 85 cases, the satisfaction index was very high (66/85 patients, very satisfactory result), higher than the classical values obtained after other treatments of face wrinkles and defects (apart from botulinum toxin effects). The complication rate was very low, with only one reversible case in this series (infection of the tip on a multi-operated nose). The durability of results was dependent on the product: 4 months for botulinum toxin, 12 to 14 months after 2 injections for resorbable fillers.

CONCLUSION

Medical rhinoplasty provides a large range of therapeutic solutions for minor corrections of nasal morphological or dynamic defects. The benefit/risk ratio for all aesthetic treatments must be high, what implies to reach the best result with the less complex, invasive and brutal protocol. This new approach for rhinoplasty fits in totally with actual patient expectations. The main inconveniences of this approach are the short durability of results and the cost of the procedure repetition.

摘要

目的

描述医学隆鼻的新技术,即联合使用填充剂和肉毒杆菌毒素而无需进行侵入性手术,通过对85例患者进行为期2年的回顾性分析来评估其有效性,并讨论这种新方法的适当适应症。

材料与方法

2006年1月至2008年1月期间,85例患者采用非手术方法治疗鼻锥体美学缺陷。纳入62名女性和23名男性,有不同的适应症:32例初次隆鼻,53例二次隆鼻矫正。58例单独使用填充剂,12例单独使用肉毒杆菌毒素,15例两种产品联合使用。肉毒杆菌毒素始终为A型毒素。对于填充剂,56例使用网状透明质酸,11例使用羟基磷灰石钙,2例使用磷酸三钙,2例使用L-聚乳酸,2例使用聚丙烯酰胺凝胶。在涂抹麻醉凝胶后注射填充剂,并在逆行追踪运动后与骨软骨接触处深部放置。手术结束时,手动塑造鼻子以改善产品分布。肉毒杆菌毒素注射按照特定方案在无麻醉下进行。治疗后立即、15天后和1个月后由患者和医生评估临床结果。满意度指数基于1个月后的3种回答:非常满意、满意、不足。

结果

在这85例病例中,满意度指数非常高(66/85例患者,结果非常满意),高于其他面部皱纹和缺陷治疗后获得的经典值(除肉毒杆菌毒素效果外)。并发症发生率非常低,本系列中仅有1例可逆病例(多次手术的鼻尖感染)。结果的持久性取决于产品:肉毒杆菌毒素为4个月,可吸收填充剂2次注射后为12至14个月。

结论

医学隆鼻为鼻形态或动态缺陷的微小矫正提供了广泛的治疗方案。所有美学治疗的获益/风险比必须很高,这意味着要用不太复杂、侵入性小且不粗暴的方案达到最佳效果。这种隆鼻新方法完全符合实际患者的期望。这种方法的主要不便之处在于结果的持久性短以及手术重复成本高。

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