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[气管吸痰期间机械通气的危重症患儿镇静评估]

[The assessment of sedation in the critically ill child on mechanical ventilation during tracheal suction].

作者信息

Cidoncha E, Mencía S, Riaño B, Urbano J, López-Herce J, Carrillo A

机构信息

Sección de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, España.

出版信息

An Pediatr (Barc). 2009 Mar;70(3):218-22. doi: 10.1016/j.anpedi.2008.10.011. Epub 2009 Feb 7.

Abstract

OBJECTIVES

To compare the changes in clinical sedation scales, bispectral index (BIS) and physiological variables occurring during tracheal suction in critically ill children.

DESIGN

Prospective, observational study in critically ill children on mechanical ventilation. BIS value, heart rate (HR), systolic blood pressure (SPB), diastolic blood pressure (DBP), modified Ramsay sedation scale score and the dose of sedative drugs were recorded before and 3 minutes after every tracheal suction.

RESULTS

A total of 83 tracheal suctions were analyzed from 46 children, 1 month to 15 years of age. Most of the children (92%) were receiving continuous infusions of fentanyl and midazolam, and 45.7% of them were receiving vecuronium. The increase in BIS, SPB and DBP values were small but statistically significant (BIS, from 51.8 to 57.3; SBP, from 92.9 to 103.1 mmHg; DBP, from 51.8 to 58.9 mmHg). There was poor correlation between the BIS, HR, SBP and DBP values before and after suction. A total of 87% of patients maintained the same Ramsay score values.

CONCLUSIONS

Tracheal suction produces a slight increase in the BIS and the BP in critically ill children who are receiving sedation by continuous infusion. Most children with adequate sedation do not need any other drugs before the tracheal suction. Physiological variables have no correlation with sedation scales or BIS values during the tracheal suction.

摘要

目的

比较危重症儿童气管吸痰期间临床镇静评分、脑电双频指数(BIS)及生理变量的变化。

设计

对接受机械通气的危重症儿童进行前瞻性观察研究。在每次气管吸痰前及吸痰后3分钟记录BIS值、心率(HR)、收缩压(SPB)、舒张压(DBP)、改良Ramsay镇静评分及镇静药物剂量。

结果

共分析了46例1个月至15岁儿童的83次气管吸痰情况。大多数儿童(92%)持续输注芬太尼和咪达唑仑,其中45.7%接受维库溴铵治疗。BIS、SPB和DBP值虽有小幅升高,但具有统计学意义(BIS从51.8升至57.3;SBP从92.9 mmHg升至103.1 mmHg;DBP从51.8 mmHg升至58.9 mmHg)。吸痰前后BIS、HR、SBP和DBP值之间的相关性较差。共有87%的患者Ramsay评分保持不变。

结论

对于持续输注镇静药物的危重症儿童,气管吸痰会使BIS和血压略有升高。大多数镇静充分的儿童在气管吸痰前无需使用其他药物。气管吸痰期间生理变量与镇静评分或BIS值无相关性。

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