通过T型迷宫中的强制选择程序诱导大鼠形成习惯以及预测试自由探索的影响。
Induction of habits in rats by a forced-choice procedure in T-maze and the effect of pre-test free exploration.
作者信息
Moustgaard Anette, Hau Jann
机构信息
Department of Experimental Medicine, University of Copenhagen and University Hospital of Copenhagen, Copenhagen N, Denmark.
出版信息
Behav Processes. 2009 Sep;82(1):104-7. doi: 10.1016/j.beproc.2009.04.011. Epub 2009 May 4.
A forced-choice procedure in T-maze designed for the induction of habits was used to induce strong habits in rats. The response choices of rats in 20 free-choice trials were compared after the rats had been subjected to 1 or 200 forced-choice trials to one side of the T-maze. After 200 forced-choice trials the rats showed a significant (p<.001) propensity for the habitual arm of the maze in the subsequent free-choice trials. The habit was at least as pronounced when analysed over the last 10 free-choice trials as when it was analysed over the first 10 free-choice trials. When the rats were given the opportunity to explore the entire maze immediately before the free-choice challenge after 200 forced-choice trials, this resulted in a large variation in the choice pattern of the individual rats, and a subgroup of rats choose the newly opened maze arm in 95-100% of the 20 free-choice trials.
一种用于诱导习惯形成的T型迷宫强制选择程序被用来在大鼠中诱导强烈的习惯。在大鼠在T型迷宫的一侧接受1次或200次强制选择试验后，比较它们在20次自由选择试验中的反应选择。经过200次强制选择试验后，大鼠在随后的自由选择试验中对迷宫的习惯臂表现出显著（p<0.001）的偏好。当分析最后10次自由选择试验时，习惯至少与分析前10次自由选择试验时一样明显。在经过200次强制选择试验后的自由选择挑战之前，当给予大鼠立即探索整个迷宫的机会时，这导致了个体大鼠选择模式的巨大差异，并且在20次自由选择试验中，有一个大鼠亚组在95%-100%的试验中选择了新开放的迷宫臂。
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