Inhibition of protein kinase CK2 induces E2F1 nuclear export, formation of p21/E2F1 complexes and suppression of DNA synthesis in normal human epidermal keratinocytes. - Suppr | 超能文献

Inhibition of protein kinase CK2 induces E2F1 nuclear export, formation of p21/E2F1 complexes and suppression of DNA synthesis in normal human epidermal keratinocytes.

作者信息

Isaeva Antonia Rumenova, Mitev Vanyo Ivanov

出版信息

J Dermatol Sci. 2009 Aug;55(2):134-6. doi: 10.1016/j.jdermsci.2009.04.001. Epub 2009 May 5.

DOI:10.1016/j.jdermsci.2009.04.001

Abstract

摘要

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1

Inhibition of protein kinase CK2 induces E2F1 nuclear export, formation of p21/E2F1 complexes and suppression of DNA synthesis in normal human epidermal keratinocytes.

J Dermatol Sci. 2009 Aug;55(2):134-6. doi: 10.1016/j.jdermsci.2009.04.001. Epub 2009 May 5.

2

The protein kinase CK2 inhibitor TBB mediates up-regulation of MEK3/6 and p38δ activities, down-regulation of ERK1/2 activity and induction of G1/S arrest in normal human epidermal autocrine proliferating keratinocytes.蛋白激酶CK2抑制剂TBB可介导正常人表皮自分泌增殖角质形成细胞中MEK3/6和p38δ活性上调、ERK1/2活性下调以及G1/S期阻滞。

J Dermatol Sci. 2011 Aug;63(2):124-6. doi: 10.1016/j.jdermsci.2011.04.005. Epub 2011 Apr 27.

3

Activation of p38- and CRM1-dependent nuclear export promotes E2F1 degradation during keratinocyte differentiation.p38和CRM1依赖性核输出的激活促进角质形成细胞分化过程中E2F1的降解。

Oncogene. 2007 Feb 22;26(8):1147-54. doi: 10.1038/sj.onc.1209894. Epub 2006 Aug 21.

4

BMP2 and BMP6 control p57(Kip2) expression and cell growth arrest/terminal differentiation in normal primary human epidermal keratinocytes.骨形态发生蛋白2和骨形态发生蛋白6控制正常人原代表皮角质形成细胞中p57（Kip2）的表达以及细胞生长停滞/终末分化。

Cell Signal. 2007 Apr;19(4):731-9. doi: 10.1016/j.cellsig.2006.09.006. Epub 2006 Oct 4.

5

Bortezomib arrests the proliferation of hepatocellular carcinoma cells HepG2 and JHH6 by differentially affecting E2F1, p21 and p27 levels.硼替佐米通过不同程度地影响E2F1、p21和p27的水平来抑制肝癌细胞HepG2和JHH6的增殖。

Biochimie. 2009 Mar;91(3):373-82. doi: 10.1016/j.biochi.2008.10.015. Epub 2008 Nov 12.

6

Stable low-level expression of p21WAF1/CIP1 in A549 human bronchogenic carcinoma cell line-derived clones down-regulates E2F1 mRNA and restores cell proliferation control.在源自A549人支气管癌细胞系的克隆中，p21WAF1/CIP1的稳定低水平表达下调E2F1 mRNA并恢复细胞增殖控制。

Mol Cancer. 2006 Jan 10;5:1. doi: 10.1186/1476-4598-5-1.

7

Synthesis of new analogs of benzotriazole, benzimidazole and phthalimide--potential inhibitors of human protein kinase CK2.苯并三唑、苯并咪唑和邻苯二甲酰亚胺新类似物的合成——人类蛋白激酶CK2的潜在抑制剂

Bioorg Med Chem. 2009 Feb 15;17(4):1573-8. doi: 10.1016/j.bmc.2008.12.071. Epub 2009 Jan 7.

8

Cyclosporine A inhibits colorectal cancer proliferation probably by regulating expression levels of c-Myc, p21(WAF1/CIP1) and proliferating cell nuclear antigen.环孢素A可能通过调节c-Myc、p21（WAF1/CIP1）和增殖细胞核抗原的表达水平来抑制结直肠癌的增殖。

Cancer Lett. 2009 Nov 18;285(1):66-72. doi: 10.1016/j.canlet.2009.05.001. Epub 2009 May 28.

9

Phosphorylation by p38 MAP kinase is required for E2F1 degradation and keratinocyte differentiation.E2F1降解和角质形成细胞分化需要p38丝裂原活化蛋白激酶进行磷酸化。

Oncogene. 2009 Jan 8;28(1):52-62. doi: 10.1038/onc.2008.354. Epub 2008 Sep 15.

10

PI3K signaling maintains c-myc expression to regulate transcription of E2F1 in pancreatic cancer cells.PI3K信号传导维持c-myc表达以调节胰腺癌细胞中E2F1的转录。

Mol Carcinog. 2009 Dec;48(12):1149-58. doi: 10.1002/mc.20569.

引用本文的文献

1

The lncRNA SLNCR Recruits the Androgen Receptor to EGR1-Bound Genes in Melanoma and Inhibits Expression of Tumor Suppressor p21.长链非编码 RNA SLNCR 在黑色素瘤中招募雄激素受体到 EGR1 结合基因，并抑制肿瘤抑制因子 p21 的表达。

Cell Rep. 2019 May 21;27(8):2493-2507.e4. doi: 10.1016/j.celrep.2019.04.101.

2

Phosphorylation of bovine papillomavirus E1 by the protein kinase CK2 near the nuclear localization signal does not influence subcellular distribution of the protein in dividing cells.蛋白激酶CK2在牛乳头瘤病毒E1的核定位信号附近对其进行磷酸化，这并不影响该蛋白在分裂细胞中的亚细胞分布。

Arch Virol. 2016 Jan;161(1):165-9. doi: 10.1007/s00705-015-2641-6. Epub 2015 Oct 14.

3

Polyamine metabolism changes in psoriasis.银屑病中多胺代谢的变化。

Indian J Dermatol. 2013 Jul;58(4):306-9. doi: 10.4103/0019-5154.113952.