Nigsch J, Graf U, Würgler F E
Mutat Res. 1977 Apr;43(1):57-64. doi: 10.1016/0027-5107(77)90131-2.
Larvae of Drosophila melanogaster were fed with caffeine, and the induced lethality was recorded using two different methods. With a wild-type strain a whole dose-response curve was obtained. The two sexes were equally sensitive. Four genetically different strains, showing different MMS sensitivities, were tested with two caffeine doses. The strains differed significantly in their caffeine sensitivity, but there existed no correlation between MMS and caffeine sensitivity.
给黑腹果蝇的幼虫喂食咖啡因，并使用两种不同方法记录诱导的致死率。对于野生型菌株，获得了完整的剂量反应曲线。两性的敏感性相同。用两种咖啡因剂量对四种遗传上不同且对甲基磺酸甲酯（MMS）敏感性不同的菌株进行了测试。这些菌株对咖啡因的敏感性差异显著，但MMS敏感性与咖啡因敏感性之间不存在相关性。
