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语后聋成年人工耳蜗植入效果的预测模型

A predictive model of cochlear implant performance in postlingually deafened adults.

作者信息

Roditi Rachel E, Poissant Sarah F, Bero Eva M, Lee Daniel J

机构信息

Department of Otolaryngology, University of Massachusetts Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.

出版信息

Otol Neurotol. 2009 Jun;30(4):449-54. doi: 10.1097/MAO.0b013e31819d3480.

DOI:10.1097/MAO.0b013e31819d3480
PMID:19415041
Abstract

OBJECTIVE

To develop a predictive model of cochlear implant (CI) performance in postlingually deafened adults that includes contemporary speech perception testing and the hearing history of both ears.

STUDY DESIGN

Retrospective clinical study. Multivariate predictors of speech perception after CI surgery included duration of any degree of hearing loss (HL), duration of severe-to-profound HL, age at implantation, and preoperative Hearing in Noise Test (HINT) sentences in quiet and HINT sentences in noise scores. Consonant-nucleus-consonant (CNC) scores served as the dependent variable. To develop the model, we performed a stepwise multiple regression analysis.

SETTING

Tertiary referral center.

PATIENTS

Adult patients with postlingual severe-to-profound HL who received a multichannel CI. Mean follow-up was 28 months. Fifty-five patients were included in the initial bivariate analysis.

INTERVENTION(S): Multichannel cochlear implantation.

MAIN OUTCOME MEASURES(S): Predicted and measured postoperative CNC scores.

RESULTS

The regression analysis resulted in a model that accounted for 60% of the variance in postoperative CNC scores. The formula is (pred)CNC score = 76.05 + (-0.08 x DurHL(CI ear)) + (0.38 x pre-HINT sentences in quiet) + (0.04 x long sev-prof HL(either ear)). Duration of HL was in months. The mean difference between predicted and measured postoperative CNC scores was 1.7 percentage points (SD, 16.3).

CONCLUSION

The University of Massachusetts CI formula uses HINT sentence scores and the hearing history of both ears to predict the variance in postoperative monosyllabic word scores. This model compares favorably with previous studies that relied on Central Institute for the Deaf sentence scores and uses patient data collected by most centers in the United States.

摘要

目的

建立一个针对语后聋成人人工耳蜗(CI)性能的预测模型,该模型纳入当代言语感知测试以及双耳的听力病史。

研究设计

回顾性临床研究。人工耳蜗植入术后言语感知的多变量预测因素包括任何程度听力损失(HL)的持续时间、重度至极重度HL的持续时间、植入时的年龄以及术前安静环境下的噪声中听力测试(HINT)句子得分和噪声中HINT句子得分。辅音-元音-辅音(CNC)得分作为因变量。为建立该模型,我们进行了逐步多元回归分析。

研究地点

三级转诊中心。

患者

接受多通道人工耳蜗植入的语后聋重度至极重度HL成年患者。平均随访时间为28个月。55名患者纳入初始双变量分析。

干预措施

多通道人工耳蜗植入。

主要观察指标

预测和测量的术后CNC得分。

结果

回归分析得出一个模型,该模型解释了术后CNC得分60%的方差。公式为(预测)CNC得分 = 76.05 + (-0.08 × (CI耳HL持续时间)) + (0.38 × 术前安静环境下HINT句子得分) + (0.04 × (双耳中任一只耳的重度至极重度HL持续时间))。HL持续时间以月为单位。预测和测量的术后CNC得分之间的平均差异为1.7个百分点(标准差,16.3)。

结论

马萨诸塞大学人工耳蜗公式使用HINT句子得分和双耳听力病史来预测术后单音节词得分的方差。该模型与之前依赖中央聋人研究所句子得分的研究相比具有优势,并且使用了美国大多数中心收集的患者数据。

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