局部和全身用皮质类固醇的过敏性超敏反应：综述
Allergic hypersensitivity to topical and systemic corticosteroids: a review.
作者信息
Baeck M, Marot L, Nicolas J-F, Pilette C, Tennstedt D, Goossens A
机构信息
Department of Dermatology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, Brussels, Belgium.
出版信息
Allergy. 2009 Jul;64(7):978-94. doi: 10.1111/j.1398-9995.2009.02038.x. Epub 2009 Mar 30.
Corticosteroids, which are potent anti-inflammatory and immunomodulator agents used in the treatment of various inflammatory diseases including allergic diseases, can in some cases produce immediate or delayed hypersensitivity reactions. This review summarizes the epidemiological and clinical characteristics of such reactions, including related diagnostic issues. It also presents a detailed analysis of the proposed immunological mechanisms including underlying cross-reactions.
皮质类固醇是用于治疗包括过敏性疾病在内的各种炎症性疾病的强效抗炎和免疫调节药物，在某些情况下可产生即刻或延迟性过敏反应。本综述总结了此类反应的流行病学和临床特征，包括相关的诊断问题。它还对提出的免疫机制进行了详细分析，包括潜在的交叉反应。
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