Jensen Annette Schophuus, Iversen Kasper, Vejlstrup Niels G, Hansen Peter Bo, Søndergaard Lars
Kardiologisk Klinik B, Rigshospitalet, DK-2100 København Ø.
Ugeskr Laeger. 2009 Apr 6;171(15):1270-5.
Congenital heart disease with left-to-right shunt can induce proliferation, vasoconstriction and thrombosis in the pulmonary vascular bed. Eventually, the patient may develop Eisenmenger syndrome defined as pulmonary arterial hypertension caused by high pulmonary vascular resistance with right-to-left shunt and cyanosis. Patients with Eisenmenger syndrome suffer a high risk of complications in connection with acute medical conditions, extra-cardiac surgery and pregnancy. This article describes the precautions that should be taken to reduce morbidity and mortality in these patients.
左向右分流型先天性心脏病可导致肺血管床出现增殖、血管收缩和血栓形成。最终，患者可能会发展为艾森曼格综合征，即由高肺血管阻力导致的肺动脉高压，伴有右向左分流和发绀。艾森曼格综合征患者在急性内科疾病、心外手术和妊娠相关方面存在较高的并发症风险。本文介绍了为降低这些患者的发病率和死亡率应采取的预防措施。
