Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People's Republic of China.
Chirality. 2010 Jan;22(1):159-64. doi: 10.1002/chir.20721.
Using chiral 1,1'-binaphthylazepine-derived amino alcohol as catalyst, the direct addition of in situ prepared arylzinc (with triphenylboroxine as aryl source) to various aryl aldehydes can afford optically active diarylmethanols in high yields and enantioselectivities (up to 96%).
使用手性 1,1'-联萘基氮杂环庚醇衍生的氨基醇作为催化剂，原位制备的芳基锌（以三苯基硼氧烷作为芳基源）与各种芳基醛直接加成，可以高收率和对映选择性（高达 96%）得到手性二芳基甲醇。
