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腮腺多形性腺瘤恶变。细针穿刺诊断病例研究。

Accessory parotid gland carcinoma ex pleomorphic adenoma. Case study diagnosed by fine needle aspiration.

作者信息

Tamiolakis Dimitrios, Chimona T S, Georgiou G, Proimos E, Nikolaidou S, Perogamvrakis G, Papadakis C E

机构信息

Department of Cytopathology, General Hospital of Chania, Crete, Greece.

出版信息

Stomatologija. 2009;11(1):37-40.

Abstract

OBJECTIVE

The accessory parotid gland is salivary tissue separated from the main parotid gland and lying on masseter muscle. It has secondary duct emptying into the Stensen's duct. The accessory parotid gland exists in 21-61% of individuals. However, the appearance of an accessory parotid tumor is rare, with a reported frequency of 1-7.7% of all parotid gland tumors. Carcinoma ex pleomorphic adenoma arises from a pre-existing benign mixed tumor. Most of these tumors will have malignant epithelial component, but not malignant stromal component. Reports of Fine Needle Aspiration Cytological (FNAC) diagnosis of malignant mixed tumor are uncommon and have been limited to cases arising in the parotid. We report a case of carcinoma ex pleomorphic adenoma of the accessory lobe of the parotid, and address the cytopathology features and pitfalls of this condition.

CASE

A 73 aged female presented with a right nontender midcheek mass. The lesion had been present 18 months, with a recent increase in size. FNA was performed and the smears demonstrated features indicative of pleomorphic adenoma admixed with findings indicative of a poorly differentiated carcinoma.

CONCLUSION

FNAC can accurately diagnose carcinoma ex pleomorphic adenoma when strongly fixed requirements are implemented.

摘要

目的

副腮腺是与腮腺主体分离并位于咬肌上的唾液腺组织。它有副导管汇入腮腺导管。副腮腺在21%至61%的个体中存在。然而,副腮腺肿瘤的出现较为罕见,据报道其发生率占所有腮腺肿瘤的1%至7.7%。多形性腺瘤恶变起源于先前存在的良性混合瘤。这些肿瘤大多会有恶性上皮成分,但没有恶性间质成分。细针穿刺抽吸细胞学(FNAC)诊断恶性混合瘤的报道并不常见,且仅限于腮腺发生的病例。我们报告一例腮腺副叶多形性腺瘤恶变病例,并阐述这种情况的细胞病理学特征及陷阱。

病例

一名73岁女性,右侧面颊中部出现无痛性肿块。该病变已存在18个月,近期增大。进行了细针穿刺抽吸,涂片显示出多形性腺瘤的特征,并伴有低分化癌的表现。

结论

当采用严格的固定要求时,FNAC能够准确诊断多形性腺瘤恶变。

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