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退伍军人慢性疼痛与处方药滥用之间的关联。

The association between chronic pain and prescription drug abuse in Veterans.

作者信息

Becker William C, Fiellin David A, Gallagher Rollin M, Barth Kelly S, Ross Jennifer T, Oslin David W

机构信息

Philadelphia VAMC, 3900 Woodland Avenue, Philadelphia, PA 19104, USA.

出版信息

Pain Med. 2009 Apr;10(3):531-6. doi: 10.1111/j.1526-4637.2009.00584.x.

DOI:10.1111/j.1526-4637.2009.00584.x
PMID:19425211
Abstract

OBJECTIVE

We sought to investigate the association between chronic pain and self-reported prescription drug abuse in a large cohort of patients referred from primary care for a behavioral health assessment.

DESIGN

We performed a cross-sectional analysis of responses to a telephone assessment administered to patients referred for a behavioral health evaluation between April 25, 2005 and October 31, 2007. We conducted descriptive statistics and investigated multivariable associations. Multivariable analyses included age, gender, race, financial status, employment, current smoking, drinking problem, past-year illicit drug use, depression, and chronic pain.

PATIENTS

Veterans referred from primary care (N = 6,377).

RESULTS

Mean age of the sample was 56.5 years with a range of 19-97. The majority of respondents was white, unmarried, and was unemployed. Nearly 5% of the sample reported past 6-month prescription drug abuse. On multivariable analysis, younger age, possible depression (odds ratio [OR] 1.9; 1.3-2.8), probable depression (OR 2.4; 1.6-3.4), smoking (OR 1.4; 1.1-1.8), illicit drug use (OR 2.8; 2.2-3.7), and chronic pain (OR 1.9; 1.4-2.5) were associated with prescription drug abuse.

CONCLUSIONS

We have identified specific variables associated with self-reported prescription drug abuse in primary care patients. Chronic pain is associated both with an indication for prescribing opioids and with abuse of prescription medications. Clinicians are encouraged to follow treatment algorithms when managing patients with chronic pain as a method for reducing misuse.

摘要

目的

我们试图在一大群因行为健康评估而从初级保健机构转诊的患者中,研究慢性疼痛与自我报告的处方药滥用之间的关联。

设计

我们对2005年4月25日至2007年10月31日期间因行为健康评估而转诊的患者进行的电话评估回复进行了横断面分析。我们进行了描述性统计并研究了多变量关联。多变量分析包括年龄、性别、种族、财务状况、就业情况、当前吸烟状况、饮酒问题、过去一年的非法药物使用情况、抑郁症和慢性疼痛。

患者

从初级保健机构转诊的退伍军人(N = 6377)。

结果

样本的平均年龄为56.5岁,范围为19 - 97岁。大多数受访者为白人、未婚且失业。近5%的样本报告过去6个月有处方药滥用情况。在多变量分析中,年龄较小、可能患有抑郁症(比值比[OR] 1.9;1.3 - 2.8)、很可能患有抑郁症(OR 2.4;1.6 - 3.4)、吸烟(OR 1.4;1.1 - 1.8)、非法药物使用(OR 2.8;2.2 - 3.7)和慢性疼痛(OR 1.9;1.4 - 2.5)与处方药滥用有关。

结论

我们已经确定了与初级保健患者自我报告的处方药滥用相关的特定变量。慢性疼痛既与开具阿片类药物的指征有关,也与处方药滥用有关。鼓励临床医生在管理慢性疼痛患者时遵循治疗算法,以此作为减少药物滥用的一种方法。

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