Muroi K, Imagawa S, Suda T, Kajii E, Otuka Y, Sakurabayashi I, Amemiya Y, Sakamoto S, Miura Y
Department of Medicine, Jichi Medical School.
Rinsho Ketsueki. 1991 Aug;32(8):909-11.
We report a 59 year old female patient who was diagnosed as having IgG kappa myeloma with hemolytic anemia and thrombocytopenia simultaneously. Although M-protein was suspected to contribute to the hemolysis, the IgG purified from the patient's serum did not bind to red blood cells. Therefore, massive non-specific binding of M-protein to blood cells might contribute to high levels of red blood cell-associated IgG and platelet-associated IgG in the patient.
我们报告了一名59岁女性患者，该患者被诊断为同时患有IgG κ型骨髓瘤以及溶血性贫血和血小板减少症。尽管怀疑M蛋白与溶血有关，但从患者血清中纯化出的IgG并未与红细胞结合。因此，M蛋白与血细胞的大量非特异性结合可能导致了该患者红细胞相关IgG和血小板相关IgG水平升高。
