金催化炔基氮杂环丙烷合成吡咯中的抗衡离子效应
Counterion effects in a gold-catalyzed synthesis of pyrroles from alkynyl aziridines.
作者信息
Davies Paul W, Martin Nicolas
机构信息
School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
出版信息
Org Lett. 2009 Jun 4;11(11):2293-6. doi: 10.1021/ol900609f.
PMID:19425591
Abstract
Aryl-substituted N-tosyl alkynyl aziridines undergo a gold-catalyzed ring expansion to afford 2,5-substituted pyrrole products. Under certain conditions, a ring-expansion and rearrangement leads to 2,4-substituted pyrroles. The reaction pathway is determined by the counterion to the gold catalyst.
摘要
芳基取代的N-对甲苯磺酰基炔基氮丙啶发生金催化的扩环反应，生成2,5-取代的吡咯产物。在某些条件下，扩环和重排会生成2,4-取代的吡咯。反应途径由金催化剂的抗衡离子决定。
Zotero 插件