由三氟甲磺酸银（AgOTf）或阳离子金（I）配合物催化的吡咯合成。
Pyrrole synthesis catalyzed by AgOTf or cationic Au(I) complexes.
作者信息
Harrison Tyler J, Kozak Jennifer A, Corbella-Pané Montserrat, Dake Gregory R
机构信息
Department of Chemistry, 2036 Main Mall, University of British Columbia, Vancouver, BC, Canada, V6T 1Z1.
出版信息
J Org Chem. 2006 Jun 9;71(12):4525-9. doi: 10.1021/jo060382c.
PMID:16749784
Abstract
Either silver trifluoromethanesulfonate or a mixture of gold(I) chloride, silver trifluoromethanesulfonate, and triphenylphosphine catalyze the formation of pyrroles from substituted beta-alkynyl ketones and amines. The reactions proceed by using 5 mol % of catalyst with yields of isolated pyrroles ranging from 13% to 92%. Sixteen examples are used to compare the effectiveness of each catalyst.
摘要
三氟甲磺酸银或氯化金（I）、三氟甲磺酸银和三苯基膦的混合物均可催化由取代的β-炔基酮和胺形成吡咯。反应使用5 mol%的催化剂进行，分离得到的吡咯产率为13%至92%。用16个实例比较了每种催化剂的效果。
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