Yang Kechao, Wang Mi, Metcalf William W
Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
J Bacteriol. 2009 Jul;191(14):4667-70. doi: 10.1128/JB.00235-09. Epub 2009 May 8.
During phenotypic characterization of various Escherichia coli mutants, we observed that DeltaphoA strains are capable of using glycerol-2-phosphate (G2P) as a sole source of phosphorus. Mutations in the ugpBAECQ operon eliminated this phenotype, suggesting that G2P is a previously unrecognized substrate for the binding protein-dependent Ugp transporter.
在对各种大肠杆菌突变体进行表型特征分析的过程中,我们观察到ΔphoA菌株能够将甘油-2-磷酸(G2P)作为唯一的磷源利用。ugpBAECQ操纵子中的突变消除了这种表型,这表明G2P是一种此前未被认识的、依赖于结合蛋白的Ugp转运蛋白的底物。