Lee Ji-Sun, Choi Jung-Hye, Oh Young-Ha
Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea.
South Med J. 2009 Jun;102(6):659-62. doi: 10.1097/SMJ.0b013e3181a39629.
Oncocytic carcinoma of the head and neck is a very rare neoplasm. It usually occurs in the parotid glands. Only 11 cases of oncocytic carcinoma of the submandibular gland have been reported, and no cases have shown distant bone metastasis. A 67-year-old man presented with a tingling sensation in both hands due to a herniated cervical disc. A whole body bone scan and PET-CT showed disseminated bone metastases. Neck CT revealed a 1.7 cm calcified left submandibular mass. The submandibular gland and bone marrow biopsies were consistent with oncocytic carcinoma. Our case is the first report of oncocytic carcinoma of the submandibular gland with disseminated bone metastases.
头颈部嗜酸细胞癌是一种非常罕见的肿瘤。它通常发生在腮腺。下颌下腺嗜酸细胞癌仅报告过11例,且无远处骨转移的病例。一名67岁男性因颈椎间盘突出症出现双手刺痛感。全身骨扫描和PET-CT显示弥漫性骨转移。颈部CT显示左侧下颌下有一个1.7 cm的钙化肿块。下颌下腺和骨髓活检结果符合嗜酸细胞癌。我们的病例是下颌下腺嗜酸细胞癌伴弥漫性骨转移的首例报告。