Nakada M, Nishizaki K, Akagi H, Masuda Y, Yoshino T
Department of Otorhinolaryngology, Okayama University Medical School, Japan.
J Oral Pathol Med. 1998 May;27(5):225-8. doi: 10.1111/j.1600-0714.1998.tb01946.x.
Oncocytes are characterized by a remarkable number of mitochondria as demonstrated by electron microscopy. Oncocytomas are very rare tumors that are usually benign and typically occur in the parotid gland. Oncocytic carcinomas are exceedingly rare in the salivary glands. We describe a 69-year-old Japanese man with an oncocytic carcinoma of the submandibular gland. We reviewed 38 articles describing oncocytic carcinoma of the head and neck that included clinicopathologic features. Oncocytic carcinomas appear to arise from benign oncocytomas, or may also arise de novo. In oncocytic carcinoma of the head and neck, the presence of distant, rather than local lymph node, metastasis is the most important prognostic indicator.
嗜酸性细胞的特征是通过电子显微镜观察显示出大量线粒体。嗜酸性细胞瘤是非常罕见的肿瘤，通常为良性，典型地发生于腮腺。嗜酸性细胞癌在唾液腺中极为罕见。我们描述了一名69岁的日本男性，患有下颌下腺嗜酸性细胞癌。我们回顾了38篇描述头颈部嗜酸性细胞癌的文章，其中包括临床病理特征。嗜酸性细胞癌似乎起源于良性嗜酸性细胞瘤，也可能原发产生。在头颈部嗜酸性细胞癌中，远处转移而非局部淋巴结转移的存在是最重要的预后指标。
