Kuzicheva E A, Gontareva N B, Simakov M B
Tsitologiia. 2009;51(3):240-6.
The possibility of prebiotic synthesis of nucleic acids components (nucleotides) has been demonstrated under condition of the space orbital stations and satellites under effect of all space radiation spectra. Since a lot of different nucleic acids components are known to be present within small space bodies, we have to investigate their chemical complication in respect with such components as nucleotides. The goal of this work is to review our results in the field of prebiotic synthesis of purine and pyrimidine nucleotides on the board of Russian space crafts. The increase in the solid reaction mixtures exposure time leads to degradation of both initial components (nucleosides) and the reaction products (nucleotides). The dominating role of heat energy in the abiogenic reactions has been revealed in laboratory (ground) experiments. Similar set of natural nucleotides has been synthesized under effect of different open space energy sources in both flight and ground experiments. The formation of 5'-nucleotides is a dominating process. All the data are discussed in the context of exobiological investigations on the Earth's orbit.
在太空轨道站和卫星的条件下,在所有空间辐射光谱的作用下,已经证明了核酸成分(核苷酸)的益生元合成的可能性。由于已知许多不同的核酸成分存在于小天体中,我们必须研究它们相对于核苷酸等成分的化学复杂性。这项工作的目的是回顾我们在俄罗斯航天器上嘌呤和嘧啶核苷酸益生元合成领域的研究结果。固体反应混合物暴露时间的增加会导致初始成分(核苷)和反应产物(核苷酸)的降解。在实验室(地面)实验中已经揭示了热能在非生物反应中的主导作用。在飞行和地面实验中,在不同的开放空间能源的作用下,已经合成了类似的天然核苷酸组合。5'-核苷酸的形成是一个主导过程。所有数据都在地球轨道的外生物学研究背景下进行了讨论。