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访谈:无病毒诱导多能干细胞的诱导

Interview: Virus-free induction of induced pluripotent stem cells.

作者信息

Nagy Andras

出版信息

Regen Med. 2009 May;4(3):351-2. doi: 10.2217/rme.09.17.

Abstract

Dr Nagy is currently a Senior Scientist at the Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Professor in the Department of Molecular Genetics at the University of Toronto and Investigator at the McEwen Centre for Regenerative Medicine. He also holds a Tier I Canada Research Chair in Stem Cells and Regeneration. His research focuses on several areas of interest, which include: functional studies of genes belonging to families with known roles in vessel formation; development of sophisticated genetic manipulation tools in the mouse model; applying genetics to cancer research; derivation, differentiation and genetic modification of both mouse and human embryonic stem cells; and reprogramming of somatic cells to pluripotent stem cells. Dr Nagy's research is currently funded by the National Cancer Institute of Canada, Genome Canada, Stem Cell Network, NSERC and the NIH.

摘要

纳吉博士目前是西奈山医院塞缪尔·伦嫩菲尔德研究所的高级科学家、多伦多大学分子遗传学系教授以及麦克尤恩再生医学中心的研究员。他还担任加拿大一级干细胞与再生领域的研究主席。他的研究集中在几个感兴趣的领域,包括:对在血管形成中具有已知作用的基因家族进行功能研究;在小鼠模型中开发先进的基因操作工具;将遗传学应用于癌症研究;小鼠和人类胚胎干细胞的衍生、分化及基因改造;以及将体细胞重编程为多能干细胞。纳吉博士的研究目前由加拿大国家癌症研究所、加拿大基因组局、干细胞网络、加拿大自然科学与工程研究理事会以及美国国立卫生研究院资助。

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