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内镜下第三脑室造瘘术中血流动力学反应的发生率及模式

Incidence and pattern of intraoperative hemodynamic response to endoscopic third ventriculostomy.

作者信息

Ganjoo P, Sethi S, Tandon M S, Chawla R, Singh D

机构信息

Department of Anaesthesiology, GB Pant Hospital, JL Nehru Marg, New Delhi - 110 002, India.

出版信息

Neurol India. 2009 Mar-Apr;57(2):162-5. doi: 10.4103/0028-3886.51285.

Abstract

BACKGROUND

In patients undergoing endoscopic third ventriculostomy (ETV), various cardiovascular changes occur in the intraoperative period.

AIM

We tried to determine a pattern in these changes and their relation to different surgical steps.

MATERIALS AND METHODS

A total of 260 patients were studied over a period of six years. Heart rate and mean arterial pressures were recorded before introduction of the endoscope and thereafter at various stages of the operation.

RESULTS

Tachycardia was the predominant observed abnormality in 20% of patients, occurring mostly during manipulations and irrigation in the third ventricle (TV). Bradycardia was seen in 12% of patients, more often during fenestration of the floor of the third ventricle.

CONCLUSIONS

Tachycardia observed during ETV may be related to hypothalamic stimulation or a rise in intracranial pressure and bradycardia may be due to stimulation of the hypothalamus or the third cranial nerve. Anticipation of these cardiovascular changes during the relevant steps of the operation can help in taking appropriate corrective action, thus preventing potentially serious complications of ETV.

摘要

背景

在接受内镜下第三脑室造瘘术(ETV)的患者中,术期中会出现各种心血管变化。

目的

我们试图确定这些变化的模式及其与不同手术步骤的关系。

材料与方法

在六年时间里共研究了260例患者。在内镜插入前以及此后手术的各个阶段记录心率和平均动脉压。

结果

20%的患者中观察到的主要异常是心动过速,大多发生在第三脑室(TV)的操作和冲洗过程中。12%的患者出现心动过缓,更多见于第三脑室底部开窗时。

结论

ETV期间观察到的心动过速可能与下丘脑刺激或颅内压升高有关,而心动过缓可能是由于下丘脑或第三对脑神经受到刺激。在手术相关步骤中预期这些心血管变化有助于采取适当的纠正措施,从而预防ETV潜在的严重并发症。

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