低剂量率近距离放射治疗后直肠尿道瘘

Rectourethral fistula following LDR brachytherapy.

作者信息

Borchers Holger, Pinkawa Michael, Donner Andreas, Wolter Timm P, Pallua Norbert, Eble Michael J, Jakse Gerhard

机构信息

Urological Clinic, University Clinic Aachen, RWTH Aachen, Aachen, Germany.

出版信息

Urol Int. 2009;82(3):365-6. doi: 10.1159/000209374. Epub 2009 May 11.

DOI:10.1159/000209374

PMID:19440030

Abstract

Modern LDR brachytherapy has drastically reduced rectal toxicity and decreased the occurrence of rectourethral fistulas to <0.5% of patients. Therefore, symptoms of late-onset sequelae are often ignored initially. These fistulas cause severe patient morbidity and require interdisciplinary treatment. We report on the occurrence and management of a rectourethral fistula which occurred 4 years after (125)I seed implantation.

摘要

现代近距离后装放疗已大幅降低了直肠毒性，并使直肠尿道瘘的发生率降至患者总数的<0.5%。因此，迟发性后遗症的症状最初往往被忽视。这些瘘管会导致患者出现严重的发病情况，需要多学科治疗。我们报告一例在碘-125粒子植入4年后发生的直肠尿道瘘的发生情况及处理过程。