Cherr G S, Hall C, Pineau B C, Waters G S
Department of General Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.
Am Surg. 2001 Feb;67(2):131-4.
Iodine-125 brachytherapy is an effective well-tolerated treatment for localized prostate cancer. Gastrointestinal complications of brachytherapy (minor rectal bleeding or tenesmus) are uncommon. Rectal ulceration or rectourethral fistulas after prostate brachytherapy are rare. We present a case of massive refractory rectal bleeding and rectourethral fistula, a complication of prostate brachytherapy never before reported. As a result of the patient's life-threatening symptoms aggressive surgical therapy was necessary.
碘-125近距离放射治疗是一种治疗局限性前列腺癌的有效且耐受性良好的方法。近距离放射治疗的胃肠道并发症（轻微直肠出血或里急后重）并不常见。前列腺近距离放射治疗后发生直肠溃疡或直肠尿道瘘的情况罕见。我们报告一例大量难治性直肠出血和直肠尿道瘘的病例，这是前列腺近距离放射治疗一种此前从未报道过的并发症。鉴于患者出现危及生命的症状，积极的手术治疗很有必要。
