Kirby Sarah E, Yardley Lucy
Centre for Clinical Applications of Health Psychology, School of Psychology, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom.
J Nerv Ment Dis. 2009 May;197(5):324-9. doi: 10.1097/NMD.0b013e3181a20866.
This study assessed whether symptoms of posttraumatic stress disorder (PTSD), health anxiety, and intolerance of uncertainty were associated with distress in members of the Ménière's Society (n = 800), and compared the extent of anxiety, depression, intolerance of uncertainty, and health anxiety with a healthy control group (n = 484). PTSD symptoms were associated with anxiety, depression, and handicap. Health anxiety was associated with anxiety and depression. Intolerance of uncertainty was directly associated with anxiety; its association with depression and handicap was mediated by PTSD symptoms. The Ménière's group reported more anxiety, depression, and health anxiety than the control group, but were not more intolerant of uncertainty. More than half of the Ménière's group reported experiencing partial or full PTSD symptoms. As PTSD, health anxiety and intolerance of uncertainty are modifiable with psychological treatment, we advise that clinicians should screen patients with Ménière's disease who are particularly distressed.
本研究评估了创伤后应激障碍（PTSD）症状、健康焦虑和对不确定性的不耐受是否与美尼尔氏病协会成员（n = 800）的痛苦相关，并将焦虑、抑郁、对不确定性的不耐受和健康焦虑程度与健康对照组（n = 484）进行了比较。PTSD症状与焦虑、抑郁和残疾相关。健康焦虑与焦虑和抑郁相关。对不确定性的不耐受与焦虑直接相关；其与抑郁和残疾的关联由PTSD症状介导。美尼尔氏病组报告的焦虑、抑郁和健康焦虑比对照组更多，但对不确定性的不耐受并不更高。超过一半的美尼尔氏病组报告经历了部分或全部PTSD症状。由于PTSD、健康焦虑和对不确定性的不耐受可通过心理治疗得到改善，我们建议临床医生应对特别痛苦的美尼尔氏病患者进行筛查。
