Ohtori Seiji, Kinoshita Tomoaki, Yamashita Masaomi, Inoue Gen, Yamauchi Kazuyo, Koshi Takana, Suzuki Munetaka, Orita Sumihisa, Eguchi Yawara, Nakamura Shinichiro, Yamagata Masatsune, Takaso Masashi, Ochiai Nobuyasu, Kishida Shunji, Aoki Yasuchika, Takahashi Kazuhisa
Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Spine (Phila Pa 1976). 2009 Jun 1;34(13):1345-8. doi: 10.1097/BRS.0b013e3181a401bf.
Randomized, controlled study.
To evaluate the diagnosis of discogenic low back pain (LBP) with discography and discoblock.
Discogenic LBP is usually diagnosed by magnetic resonance imaging and discography. However, the reliability of discography is controversial. Previously, we reported the usefulness of discoblock with bupivacaine for diagnosis, and discoblock improved the results of anterior interbody fusion surgery. However, that study was not a randomized, controlled study. Therefore, the purpose of the current study was to compare the results of surgery after diagnosis of LBP by discography and discoblock.
Patients (n = 42) with severe LBP showing L4-L5 or L5-S1 disc degeneration on magnetic resonance imaging were evaluated by discography (1.5 mL of contrast medium) or discoblock (intradisc injection of 0.75 mL of 0.5% bupivacaine). We randomized the patients in turn. Anterior discectomy and interbody fusion were performed in patients who responded to the diagnostic procedures. The visual analogue scale score (0, no pain; 100, worst pain), Japanese Orthopedic Association Score (0, worst pain; 3, no pain), Oswestry Disability Index, and patient satisfaction before and 3 years after surgery were recorded and compared between groups.
Twelve patients did not show pain provocation by discography or pain relief by discoblock and were excluded. Fifteen patients who showed pain provocation by discography and 15 patients who experienced pain relief with discoblock were evaluated. Rates of improvement in the visual analogue scale score, Japanese Orthopedic Association Score, and Oswestry Disability Index score in the discoblock group were significantly higher than those in the discography group (P < 0.05) from baseline to 3 years after surgery. Three patients were dissatisfied with surgery after discography compared with one patient after discoblock.
Pain relief after injection of a small amount of bupivacaine into the painful disc was a useful tool for the diagnosis of discogenic LBP compared with discography.
随机对照研究。
通过椎间盘造影和椎间盘阻滞评估椎间盘源性下腰痛(LBP)的诊断。
椎间盘源性LBP通常通过磁共振成像和椎间盘造影进行诊断。然而,椎间盘造影的可靠性存在争议。此前,我们报道了布比卡因椎间盘阻滞在诊断中的有用性,且椎间盘阻滞改善了前路椎间融合手术的效果。然而,该研究并非随机对照研究。因此,本研究的目的是比较经椎间盘造影和椎间盘阻滞诊断LBP后手术的结果。
对磁共振成像显示L4-L5或L5-S1椎间盘退变的重度LBP患者(n = 42)进行椎间盘造影(注射1.5 mL造影剂)或椎间盘阻滞(椎间盘内注射0.75 mL 0.5%布比卡因)评估。我们依次将患者随机分组。对诊断性操作有反应的患者进行前路椎间盘切除和椎间融合术。记录并比较两组患者手术前后的视觉模拟评分(0分,无疼痛;100分,最严重疼痛)、日本骨科协会评分(0分,最严重疼痛;3分,无疼痛)、Oswestry功能障碍指数以及患者满意度。
12例患者经椎间盘造影未出现疼痛激发或经椎间盘阻滞未出现疼痛缓解,被排除。对15例经椎间盘造影出现疼痛激发的患者和15例经椎间盘阻滞疼痛缓解的患者进行了评估。从基线到术后3年,椎间盘阻滞组的视觉模拟评分、日本骨科协会评分和Oswestry功能障碍指数评分的改善率显著高于椎间盘造影组(P < 0.05)。与椎间盘阻滞后1例患者不满意手术相比,椎间盘造影后有3例患者对手术不满意。
与椎间盘造影相比,向疼痛椎间盘内注射少量布比卡因后疼痛缓解是诊断椎间盘源性LBP的一种有用方法。