Cao Yuan-Cheng, Wang Zhan, Wang Hai-Qiao, Wang Jian-Hao, Hua Xiao-Feng, Jin Xin, Yang Liang, Huang Zhen-Li, Liu Man-Xi, Zhao Yuan-Di
Key Laboratory of Biomedical Photonics of Ministry of Education - Wuhan National Laboratory for Optoelectronics, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, PR China.
J Nanosci Nanotechnol. 2009 Mar;9(3):1778-84. doi: 10.1166/jnn.2009.396.
A novel quantum dots (QDs) fluorescent encoding method was demonstrated in this paper by using Au coated polystyrene (Au @ PS) beads. In the experiments, Au nanoparticles were deposited onto the polystyrene bead to form a stable Au coating through Layer-by-Layer assembly, and the surface morphology of the Au @ PS beads was studied by Scanning Electronic Microscope (SEM). Furthermore, the QDs encoding abilities, including the loading of QDs, the anti-photo bleaching ability and the multi-color encoding feasibility were studied using Au @ PS beads. The QDs leakage from doped QDs encoded Au @ PS was also studied. This study shows that Au particles improve the QDs encoding performance and the QD-encoded Au @ PS beads are the ideal material for the optical encoding.
本文展示了一种通过使用金包覆聚苯乙烯(Au@PS)微球的新型量子点(QDs)荧光编码方法。在实验中,通过层层组装将金纳米颗粒沉积到聚苯乙烯微球上以形成稳定的金涂层,并利用扫描电子显微镜(SEM)研究了Au@PS微球的表面形态。此外,使用Au@PS微球研究了量子点的编码能力,包括量子点的负载、抗光漂白能力和多色编码可行性。还研究了掺杂量子点的Au@PS中量子点的泄漏情况。该研究表明金颗粒提高了量子点的编码性能,且量子点编码的Au@PS微球是光学编码的理想材料。