Mohammed Asim A, Januzzi James L
Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA.
Curr Clin Pharmacol. 2009 May;4(2):87-94. doi: 10.2174/157488409788184945.
BNP or NT-proBNP testing has dramatically changed the management of acute heart failure patients by aiding in early recognition, prognostication and treatment. Furthermore, recent studies have shown that natriuretic peptide testing may guide the therapy of the stable chronic heart failure patients in out-patient setting. We will review the understanding of utilizing natriuretic peptide testing to guide heart failure therapy, including present and future directions for this exciting area.
B型利钠肽(BNP)或N末端B型利钠肽原(NT-proBNP)检测通过辅助早期识别、预后评估及治疗,极大地改变了急性心力衰竭患者的管理方式。此外,近期研究表明,利钠肽检测可能有助于指导门诊稳定期慢性心力衰竭患者的治疗。我们将回顾利用利钠肽检测指导心力衰竭治疗的相关认识,包括这一令人兴奋领域的现状及未来发展方向。