Kim Yong-Sam, Yoo Hyang Sook, Ko Jeong Heon
Daejeon-KRIBB-FHCRC Research Cooperation Center, KRIBB, 111 Gwahangno, Yuseong-gu, Daejeon, Korea.
Protein Pept Lett. 2009;16(5):499-507. doi: 10.2174/092986609788167798.
Aberrant glycosylation is frequently found in cancer, and efforts for biomarker discovery include the preparation of aberrant glycoproteins as promising analytes. Several lectins that bind to aberrant glycans and can be thus used to capture and enrich aberrant glycoproteins in the frontal stage during biomarker discovery are to be introduced.
异常糖基化在癌症中经常被发现，生物标志物发现方面的工作包括制备异常糖蛋白作为有前景的分析物。本文将介绍几种能与异常聚糖结合、从而可用于在生物标志物发现前期捕获和富集异常糖蛋白的凝集素。
