Walsh David J, Sills Eric Scott, Shkrobot Lyuda V, Gleeson Noreen C, Sheppard Mary N, Walsh Anthony P H
Department of Obstetrics and Gynaecology, Division of Reproductive Endocrinology and Infertility, School of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
World J Surg Oncol. 2009 May 14;7:46. doi: 10.1186/1477-7819-7-46.
To present a diagnostic evaluation and treatment strategy for serous adenocarcinoma of the ovary discovered during an in vitro fertilisation (IVF) sequence, and report on reproductive outcome after tumour resection and embryo transfer.
Cycle monitoring in IVF identified an abnormal ovarian lesion which was subjected to ultrasound-guided needle aspiration. Cytology suggested malignancy, and unilateral oophorectomy was performed after formal staging. After surgery, the patient underwent an anonymous donor oocyte IVF cycle which established a viable twin intrauterine pregnancy. No recurrence of cancer has been detected in the >72 month follow-up interval; mother and twin daughters continue to do well.
Suspicious adnexal structures noted during controlled ovarian hyperstimulation for IVF warrant assessment, and this report confirms the role of aspiration cytology in such cases. If uterine conservation is possible, successful livebirth can be achieved from IVF if donor oocyes are utilised, as described here.
介绍在体外受精（IVF）过程中发现的卵巢浆液性腺癌的诊断评估和治疗策略，并报告肿瘤切除及胚胎移植后的生殖结局。
IVF周期监测发现一个异常卵巢病变，对其进行了超声引导下针吸活检。细胞学检查提示为恶性肿瘤，在进行正式分期后实施了单侧卵巢切除术。术后，患者接受了匿名供者卵母细胞IVF周期，成功建立了双胎宫内妊娠。在超过72个月的随访期内未检测到癌症复发；母亲和双胞胎女儿情况良好。
在IVF控制性卵巢刺激过程中发现的可疑附件结构需要进行评估，本报告证实了针吸细胞学在此类病例中的作用。如果可以保留子宫，如本文所述，利用供者卵母细胞进行IVF可成功实现活产。
