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[以臂桡侧瘙痒为表现的室管膜瘤]

[Brachioradial pruritus revealing an ependymoma].

作者信息

Fleuret C, Dupré-Goetghebeur D, Person H, Pillette-Delarue M, Conan-Charlet V, Mériot P, Esnault-Lavandier C, Misery L

机构信息

Service de dermatologie, CHU de Brest, 29609 Brest cedex, France.

出版信息

Ann Dermatol Venereol. 2009 May;136(5):435-7. doi: 10.1016/j.annder.2008.11.020. Epub 2009 Apr 25.

Abstract

BACKGROUND

Brachioradial pruritus is a rare form of pruritus localised to one or more brachioradial dermatomes, initially classified as a photodermatosis but which in fact is generally brought on by nervous compression. We report a case of a brachioradial pruritus revealing an intramedullary tumour.

PATIENTS AND METHODS

A 53-year-old man had presented pruritus for seven years under the left clavicle, then on the left forearm followed by the right forearm. Finally cervicodynia appeared associated with dysaesthesia of the two upper limbs, fulgurating pains and paresis of the left cubital region. The examination revealed suspended bilateral hypoaesthesia (C4, C5, C6, C7), proprioceptive disorders of the left upper limb, mild motor deficit in the left C8 area and tetrapyramidal syndrome. Cervical radiography did not show cervical osteoarthritis. The MRI revealed a bulky cervical intramedullary tumour extending from C2 to C6. After ruling out cavernoma by medullary angiography, surgery was performed and histopathological analysis of the complete lesion revealed a benign ependymoma. Four months later, this patient complained about residual pains requiring treatment with gabapentin and class 2 analgesics.

DISCUSSION

The case presented underlines the possibility of a brachioradial pruritus revealing an intramedullary tumour. Ependymomas are usually seen in children and are frequently evoked in the presence of dysaesthesia. We report the third case of brachioradial pruritus revealing a medullary tumour. The two other cases involved syringomyelia revealed by pruritus in C5 and ependymoma revealed by pruritus in C5-C6. The patient with ependymoma had refused surgical treatment.

CONCLUSION

Atypical brachioradial pruritus complicated by neuropathic pains and disorders should prompt screening for a medullary tumour.

摘要

背景

臂桡侧瘙痒症是一种罕见的瘙痒症,局限于一个或多个臂桡侧皮节,最初被归类为光皮肤病,但实际上通常由神经受压引起。我们报告一例臂桡侧瘙痒症并发髓内肿瘤的病例。

患者与方法

一名53岁男性,左侧锁骨下瘙痒7年,随后左侧前臂、右侧前臂也出现瘙痒。最终出现颈痛,并伴有双上肢感觉异常、电击样疼痛和左侧肘区轻瘫。检查发现双侧感觉减退(C4、C5、C6、C7)、左侧上肢本体感觉障碍、左侧C8区轻度运动功能缺损和锥体束征。颈椎X线检查未显示颈椎骨关节炎。MRI显示一个巨大的颈髓内肿瘤,从C2延伸至C6。经髓内血管造影排除海绵状血管瘤后,进行了手术,对完整病变的组织病理学分析显示为良性室管膜瘤。四个月后,该患者抱怨残留疼痛,需要使用加巴喷丁和2类镇痛药治疗。

讨论

该病例强调了臂桡侧瘙痒症并发髓内肿瘤的可能性。室管膜瘤通常见于儿童,在感觉异常的情况下常被提及。我们报告第三例臂桡侧瘙痒症并发髓内肿瘤的病例。另外两例分别是C5区瘙痒并发脊髓空洞症和C5 - C6区瘙痒并发室管膜瘤。患有室管膜瘤的患者拒绝了手术治疗。

结论

伴有神经性疼痛和功能障碍的非典型臂桡侧瘙痒症应促使对髓内肿瘤进行筛查。

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