电针视觉相关穴位与非视觉相关穴位所诱导的视觉皮层激活的比较。

Comparison of visual cortical activations induced by electro-acupuncture at vision and nonvision-related acupoints.

作者信息

Zhang Yi, Liang Jimin, Qin Wei, Liu Peng, von Deneen Karen M, Chen Peng, Bai Lijun, Tian Jie, Liu Yijun

机构信息

Life Science Research Center, School of Electronic Engineering, Xidian University, Xi'an, Shaanxi 710071, China.

出版信息

Neurosci Lett. 2009 Jul 10;458(1):6-10. doi: 10.1016/j.neulet.2009.04.027. Epub 2009 Apr 15.

DOI:10.1016/j.neulet.2009.04.027

PMID:19442868

Abstract

In the current study, we investigated whether or not stimulation at vision and nonvision-related acupoints was able to induce similarity in the time domain, although stimulation at different acupoints could produce similar spatial distributions. This phenomenon still remains uncertain and contradictory. We introduced a novel experimental paradigm using a modified non-repeated event-related (NRER) design, and utilized the methods of independent component analysis (ICA) combined with seed correlated functional connectivity analysis to locate visual cortical activations and to study their temporal characteristics during electro-acupuncture (EAS) at vision-related acupoint GB 37 and nonvision-related acupoint KI 8. Results showed that strong activations were present in the visual cortical areas (BA 17/18/19) at both acupoints, but temporal correlation analysis indicated that they were modulated in opposite directions during the resting state after acupuncture. Our results revealed that acupuncture at vision and nonvision-related acupoints can induce similar activations in spatial distribution but different modulation effects temporally.

摘要

在本研究中，我们探究了尽管刺激不同穴位可产生相似的空间分布，但刺激视觉相关穴位和非视觉相关穴位是否能够在时域中诱导出相似性。这一现象仍然不确定且存在矛盾。我们引入了一种使用改良的非重复事件相关（NRER）设计的新型实验范式，并利用独立成分分析（ICA）结合种子相关功能连接分析的方法来定位视觉皮层激活，并研究在电针刺激视觉相关穴位足少阳胆经37穴和非视觉相关穴位足少阴肾经8穴时它们的时间特征。结果表明，在两个穴位处视觉皮层区域（BA 17/18/19）均出现强烈激活，但时间相关性分析表明，针刺后静息状态下它们的调制方向相反。我们的结果表明，针刺视觉相关穴位和非视觉相关穴位在空间分布上可诱导相似的激活，但在时间上具有不同的调制效应。